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Understanding the mechanisms of idiopathic pulmonary fibrosis in order to develop new treatments
IPF is a progressive and devastating lung disorder characterised by irreversible scarring (fibrosis) of the lung. IPF affects over 8,000 peo
Glenn Hearson
Nov 7, 2016


Creating “Breathing” Lung Slices in the Laboratory
Many research groups around the world use thin slices of lung tissue to investigate asthma and other respiratory diseases. Lung slices...
Glenn Hearson
Nov 4, 2016


Klaudia Kaczmarek: Inhibiting PMRTs in Asthma
Klaudia Kaczmarek is a PhD student working in Nottingham City Hospital, supervised by Professor Alan Knox and Dr Rachel Clifford . Her...
Glenn Hearson
Oct 27, 2016


Amanda Goodwin: Targeting Myofibroblast Mechanotransduction to prevent Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) is a long-term chest condition that is characterised by fibrosis (scarring) of the lungs, which...
Glenn Hearson
Oct 21, 2016


Rachel Clifford: Epigenetics of Lung Disease
I am interested in the epigenetics of lung disease, primarily asthma. Epigenetics refers to a group of processes that control how and...
Glenn Hearson
Oct 21, 2016


Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) is a devastating, progressive disease with poor survival rates and limited treatment options. Upregulati
Glenn Hearson
Sep 4, 2016


Caffeine inhibits TGFβ activation in epithelial cells, interrupts fibroblast responses to TGFβ
Caffeine inhibits TGFβ activation in epithelial cells, interrupts fibroblast responses to TGFβ
Glenn Hearson
Jul 15, 2016


Reduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin αvβ6
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease with high mortality. Active TGFβ1 is considered central to the pa
Glenn Hearson
May 28, 2016
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