• Glenn Hearson

Benralizumab study ANDHI shows early clinical benefits in #severe asthma patient-reported outcomes

Between 2017 and 2019, Liz Dark and our asthma team, led by Professor Tim Harrison of the NIHR Nottingham BRC, recruited severe asthma patients into the phase 3b #ANDHI study treating patients with #Benralizumab.


ANDHI was done to assess the efficacy of #benralizumab, including onset of effect and impact on health-related quality of life (HRQOL), exacerbation rate, lung function, and nasal polyposis symptoms.


The latest results have recently been published in the #Lancet, "Onset of effect and impact on health-related quality of life, exacerbation rate, lung function, and nasal polyposis symptoms for patients with severe eosinophilic asthma treated with benralizumab (ANDHI): a randomised, controlled, phase 3b trial"; https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(20)30414-8/fulltext


Interpretation

the results extend the efficacy profile of #benralizumab for patients with severe eosinophilic asthma, showing early clinical benefits in patient-reported outcomes, HRQOL, lung function, and nasal polyposis symptoms.




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